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Author Archives: Lennart Hilbert
Timing zygotic genome activation
Today, our review on the temporal regulation of zygotic genome activation was published in Current Opinion in Genetics and Development. The review is part of a themed issue of genome architecture and expression, edited by Bart Deplancke and Charles Sagerstrom and contains many more interesting reviews. For the first 50 days, you can download our review for free.
And of course, a little celebration.
EMBO Workshop: Maternal-to-Zygotic Transition
The MPI-CBG will host the EMBO Workshop “Awakening of the Genome: The Maternal-to-Zygotic Transition” from 23rd to 26th of April, 2017.
Nadine Vastenhouw and her co-organizers Philip Zegerman, Howard Lipshitz, and Petr Svoboda will be hosting an eclectic roster of international experts cutting across disciplines, techniques, and model systems.
To learn more about the speakers, programme, and – of course – to register, please visit http://events.embo.org/17-mzt/
Feel free to print and display the workshop poster (here as full definition PDF).
Camilo Riquelme Guzmán
Camilo is from Santiago, Chile, a big city surrounded by hills and mountains (next to the Andes!). Here he pursued his undergraduate studies at the University of Chile and, in his second year, joined a microbiology laboratory (BEM) where he learned about peptide antibiotics. After that, he decided to jump from prokaryotic to eukaryotic and joined Enrique Brandan’s lab at the Catholic University of Chile, where he studied the role of the extracellular matrix in muscle fibrosis. Throughout the 4 years that he spent there, he became very interested in development and decided to make a big change in 2016. He moved 12,500 kilometers to Dresden to join Nadine Vastenhouw’s lab at MPI-CBG as a PhD student. Currently, Camilo is investigating the role of chromatin structure in the regulation of zygotic genome activation in zebrafish. In his free time, he likes outdoor activities such as climbing and biking, or just going out to see the wonders of nature.
Thesis Defense Carine
As the first Vastenhouw Lab Predoc student, Carine has successfully defended her thesis. Congratulations Carine, also on the impressive “Doktorhut” (special German version of the PhD graduation hat).
Genome Architecture Meeting at ICTP, Trieste
Lennart participated in the meeting “Genome Architecture in Space and Time”, which took place at the International Center for Theoretical Physics in Trieste from June 20th to 24th. The venue would suggest a Physics and Theory heavy meeting – and certainly there was some of that – but the conference covered various aspects of genome architecture. From newest biophysical and imaging approaches, via medical relevance of aberrations in genomic structural elements, to polymer folding models, a truly eclectic mix of questions and approaches was presented. Unusual for an international meeting, the invited speakers had about 45 minutes each. Throughout, this time was put to good use, allowing comprehensive introductions, sometimes reaching back decades to lead up to the most up-to-date questions.
FISHing fish, explained on thenode
Our recent publication is covered in a piece on FISHing fish. Check out the description and a bit of a behind-the-scenes insight into of the paper!
Paper reference:
Stapel, L Carine; Lombardot, Benoit; Broaddus, Coleman; Kainmueller, Dagmar; Jug, Florian; Myers, Eugene W.; Vastenhouw, Nadine L.
Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos
Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos
Development, 143, no. 3, pp. 540-546, (2016)