The One with the Goose

The legend goes that St. Martin once gave a homeless person half his coat, and saved them from the cold. With this good deed, the Church officials wanted to honour St. Martin by ordaining him as the next bishop. Being a modest man, he hid in a goose pen to avoid the Church officials. Well, the cackling of the geese betrayed him and the goose became the symbol of St. Martin’s day.

The lab celebrated the German tradition of Martinsgans (St. Martin’s goose) over a festive meal: roasted goose, Knudeln (German dumplings), Wurst (sausage), Flammkuchen (flame cake, German flatbread), and Kartoffeltasche (potato bag).

We also welcomed our guest for the week, Dr. Haruka Oda, a postdoctoral fellow from the lab of Dr. Hiroshi Kimura at Tokyo Institute of Technology.

Book chapter on how to smFISH in zebrafish embryos

Interested in detecting single transcripts from zebrafish embryos? or applying smFISH to your research?

Carine’s chapter in Methods in Molecular Biology is out!

The chapter provides a detailed protocol: from setting up the embryos to cryosection, to smFISH, to image analysis.

You’ll also find a description of the pipeline for membrane segmentation and transcription detection.

Visit Book Chapter at Methods in Molecular Biology

Máté: Submit thesis ✓

Máté reached an important milestone of his PhD studies – thesis submission! High-Five Máté for crunching your way through thesis writing and making it through!

Next up: thesis defense.

PhD defense: Dr. Shai Joseph

 

 

2017.10.30: Congratulations Shai on successfully defending his PhD!

Many thanks to our artistically talented Sabrina for making Shai’s fantastic Doktorhut,

which features past and current lab members partying at “Shai’s Histone Cocktail Bar” atop the hat.

All the best to Shai in his new career path!

 

 

Photo credit (top featured image): IMPRS PhD program

Lennart presents at CBG’s Friday Seminar

20.10.2017: With ~3 years of research experience at CBG up his sleeve, it was now Lennart’s time to take centre stage and present his research to the CBG community at the internal Friday Seminar series. The showcase was followed by social hour with fellow scientists. We capped our Friday off with a belated birthday celebration over delicious burgers.

 

Lab Retreat 2017

Tis that time of the year again! This year’s Vastenhouw Lab retreat took place in Technische Universität (TU) Dresden’s Computer Science green building. Together with Vasily Zaburdaev (MPI-PKS) and Thomas Quail (Jan Brugues lab, MPI-CBG), we had a matinee of stimulating and fruitful discussions.

In the evening, we all gathered around a kitchen and bar – where we got to cook our dinner and shake our cocktails (with some help from the professionals). A festive night for the Vastenhouw Lab! There were also hellos and goodbyes. We welcomed new lab members and said farewell to the veterans, as they transition to the next chapter of their career.

        

 

eLife Paper on Refractive Index Matching in Live Imaging

Microscopes are optimized to give the clearest images, taking great care of all optical components along the light path. This has lead to a situation where the transition between a live sample and the surrounding liquid becomes the biggest imperfection in the optical path.

In this MPI-CBG/MPI-PKS/CSBD collaboration, lead by Tobias Boothe from the Rink lab, we show a simple but highly effective procedure to minimize the optical imperfection at the sample/medium interface. The technique is based on OptiPrep (chemical name: iodixanol), which can be ordered and used in any biological laboratory without any unusual equipment. Our technique worked with no toxicity or other problems in whole animals, primary cells, cell lines, as well as organoids.

Find our paper online with eLife.

Edlyn at MPI-CBG Postdoc Retreat

Edlyn attended the 7th Annual MPI-CBG Postdoc Retreat, which took place in the beautiful and picturesque Tisá, Czech Republic, from 19th to 21st of June, 2017.

The three-day retreat included talks (and elevator pitches) from fellow postdocs at the institute & invited external speakers:

  • Dr. Simon Reber (Humboldt-Universität, Berlin),
  • Dr. Elvan Boke (Centre for Genomic Regulation, Barcelona),
  • Dr. Selina Wray (University College London),
  • Dr. Adrian Raga (Katholieke Universiteit Leuven),
  • Dr. Olof Idevall-Hagren (Uppsala University);

and talks from our very own: Dr. Jacqueline Tabler and Dr. Christoph Zechner.

The retreat was scientifically enriching and also featured a hiking trip in Bohemian Switzerland, through the sandstone rocks of the Tisá Walls.

2017-06-20 15.48.04     

Science outreach – for juniors and seniors

Last month Pavel, Lennart, and Máté shared their enthusiasm for science as part of the “Junior Doktor” and “Seniorenakademie” series at our institute.

Pavel taught highly motivated pupils from primary school about the evolution of the eye. This was followed up by a microscopy session where the ‘scientists of the future’ got to look at zebrafish pineal glands and stained nuclei of zebrafish embryos.

Máté gave a seminar about transcription factors to an excited elder audience. He talked about general concepts of how transcription factors can orchestrate gene expression programs with some examples from his own research in zebrafish.