Camilo Riquelme Guzmán

Camilo is from Santiago, Chile, a big city surrounded by hills and mountains (next to the Andes!). Here he pursued his undergraduate studies at the University of Chile and, in his second year, joined a microbiology laboratory (BEM) where he learned about peptide antibiotics. After that, he decided to jump from prokaryotic to eukaryotic and joined Enrique Brandan’s lab at the Catholic University of Chile, where he studied the role of the extracellular matrix in muscle fibrosis. Throughout the 4 years that he spent there, he became very interested in development and decided to make a big change in 2016. He moved 12,500 kilometers to Dresden to join Nadine Vastenhouw’s lab at MPI-CBG as a PhD student. Currently, Camilo is investigating the role of chromatin structure in the regulation of zygotic genome activation in zebrafish. In his free time, he likes outdoor activities such as climbing and biking, or just going out to see the wonders of nature.

Thesis Defense Carine

Carine sporting her "Doktorhut"

As the first Vastenhouw Lab Predoc student, Carine has successfully defended her thesis. Congratulations Carine, also on the impressive “Doktorhut” (special German version of the PhD graduation hat).

Genome Architecture Meeting at ICTP, Trieste

Lennart participated in the meeting “Genome Architecture in Space and Time”, which took place at the International Center for Theoretical Physics in Trieste from June 20th to 24th. The venue would suggest a Physics and Theory heavy meeting – and certainly there was some of that – but the conference covered various aspects of genome architecture. From newest biophysical and imaging approaches, via medical relevance of aberrations in genomic structural elements, to polymer folding models, a truly eclectic mix of questions and approaches was presented. Unusual for an international meeting, the invited speakers had about 45 minutes each. Throughout, this time was put to good use, allowing comprehensive introductions, sometimes reaching back decades to lead up to the most up-to-date questions.

Carine Stapel attends the MBL Embryology Course 2016

From June 4 to July 17 Carine joined the MBL Embryology course in Woods Hole. This course has a longstanding tradition (since 1893) in teaching students, postdocs and faculty the nuts and bolts of developmental biology. From C. elegans, chick and ctenophore to sea urchin, snails and squid (and zebrafish of course!), the morning lectures and experiments that lasted until the wee hours of the night covered them all. Now let’s see if she can convince the Vastenhouw lab to add some new species to its repertoire! 

Pavel visits the lab of Prof. Tatjana Sauka-Spengler in Oxford

In mid-March 2016, Pavel visited the lab of our collaborator Prof. Tatjana Sauka-Spengler in Oxford, UK. Tatjana’s lab established a genetically encoded system for biotinylation of specific targets in fish cells, allowing, among other applications, tissue-specific isolation of nuclei.

Supervised by a cheerfully enthusiastic PhD student Vanessa Chong, Pavel performed several rounds of nuclei isolation and is looking forward to introduce this method to Vastenhouw lab. 

Apart from having great time in Tatjana’s lab, Pavel also explored the charming campus of the Oxford University.

Thanks the entire Sauka-Spengler lab for a great time!

Setting up the experiment

Pavel’s Birthday

The Vastenhouw Lab celebrated Pavel's birthday with delicious bakery goods from the Czech Republic.  Gastrulating zebrafish embryos made from Play-Doh were an absolute must for the celebration.

Segmented Cells

FISHing fish, explained on thenode

Our recent publication is covered in a piece on FISHing fish. Check out the description and a bit of a behind-the-scenes insight into of the paper!

Link to post on thenode

Paper reference:

Stapel, L Carine; Lombardot, Benoit; Broaddus, Coleman; Kainmueller, Dagmar; Jug, Florian; Myers, Eugene W.; Vastenhouw, Nadine L.
Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos
Development, 143, no. 3, pp. 540-546, (2016)